Status:
UNKNOWN
National Cohort of Uncomplicated Alcoholic Cirrhosis
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
National Cancer Institute, France
French National Agency for Research on AIDS and Viral Hepatitis
Conditions:
Alcoholic Cirrhosis
Eligibility:
All Genders
18+ years
Brief Summary
Hepatocellular carcinoma (HCC) is a major public health problem, whose incidence is increasing in developed countries and is the leading cause of death in patients with cirrhosis. The diagnosis and th...
Detailed Description
Patients will be selected for the study if they met all the inclusion criteria, without any of the non-inclusion criteria, ie compensated Child Pugh A alcoholic cirrhosis without viral chronic hepatit...
Eligibility Criteria
Inclusion
- age ≥ 18 years
- histologically proven cirrhosis
- no previous HCC (treated or not )
- excessive consumption of alcohol, considered as the main cause of cirrhosis
- signed informed consent.
Exclusion
- serious associated short-term life threatening disease (except associated HIV viral infection and the liver disease itself),
- decompensation of cirrhosis (bleeding or ascites),
- co-infection with HBV or HCV;
- liver focal lesion suggestive of HCC
- Child Pugh score ≥ 7 (Class B or C).
- patient under guardianship
- pregnant women
- inability to regular monitoring, for whatever reason
Key Trial Info
Start Date :
October 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2021
Estimated Enrollment :
709 Patients enrolled
Trial Details
Trial ID
NCT01213927
Start Date
October 1 2010
End Date
October 1 2021
Last Update
February 19 2019
Active Locations (1)
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1
Jean Verdier hospital (AP-HP)
Bondy, France, 93140