Status:

COMPLETED

The Effect of Heparin in Treatment IVF-ET Failure

Lead Sponsor:

Yazd Medical University

Collaborating Sponsors:

Yazd Research & Clinical Center for Infertility

Conditions:

Pregnancy

Thrombophilia

Eligibility:

FEMALE

19-35 years

Phase:

PHASE4

Brief Summary

Embryo transfer failure is defined as ≥3 IVF-embryo transfer failures without pregnancy . In spite of transfer of 3 good quality embryos , just 20-30% of women undergoing IVF will achieve ongoing preg...

Detailed Description

Introduction Embryo transfer failure is defined as ≥3 IVF-embryo transfer failures without pregnancy . In spite of transfer of 3 good quality embryos , just 20-30% of women undergoing IVF will achieve...

Eligibility Criteria

Inclusion

  • Patients who were 19-35 years old
  • basal FSH \< 10 IU/l
  • body mass index ( BMI ) \< 29 Kg/m²
  • presence of both ovaries
  • three or more pervious IVF-ET failures
  • Top-quality embryos for transfer .

Exclusion

  • Women with polycystic ovary syndrome ( PCOS)
  • endometriosis
  • hydrosalpinx
  • chronic systemic disease( liver, renal , thyroid and thrombocytopenia ) ●Abnormal uterine cavity
  • sever male factor ( azospermia )
  • Patients who had contraindication for unfractionated heparin therapy .

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

86 Patients enrolled

Trial Details

Trial ID

NCT01214772

Start Date

May 1 2009

End Date

June 1 2010

Last Update

October 5 2010

Active Locations (1)

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Yazd Research and Clinical Centre for Infertility

Yazd, Yazd Province, Iran, 8916877391