Status:
COMPLETED
Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
London School of Hygiene and Tropical Medicine
Medical Biotech Laboratories
Conditions:
Malaria
Schistosomiasis
Eligibility:
All Genders
1+ years
Brief Summary
A longitudinal study on immune responses in relation to protection against clinical malaria episodes will be conducted in Apac District, Uganda. Three cohorts will be recruited: children 1 to 5 years ...
Eligibility Criteria
Inclusion
- age 1-5 years, 6-10 years or 25 yearsand above
- written informed consent must be given
- the individual must have been resident of the area since birth or for a minimum period of two years
- the individual must be willing to submit required information and to participate in repeated sampling (total blood volume \~2.5 mL over a period of 12 months)
- Absence of danger signs (as defined by WHO) or clinical features of AIDS. An HIV-test will be offered to all participants at enrolment and completion of the study.
Exclusion
- unwillingness to sign consent form
- unwillingness to reside in the study area during the follow-up period
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2011
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT01214876
Start Date
August 1 2010
End Date
March 1 2011
Last Update
March 4 2011
Active Locations (1)
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1
Medical Biotech Laboratories
Kampala, Uganda