Status:

COMPLETED

Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents

Lead Sponsor:

Stanford University

Conditions:

Obesity

Eligibility:

All Genders

11-17 years

Phase:

NA

Brief Summary

Large studies of children show that over half of the children in the United States of America do not have enough vitamin D stored in their bodies. In children who are overweight or obese, the percenta...

Detailed Description

Supplementation with vitamin D at 150,000 IU every 3 months failed to increase serum 25-hydroxy vitamin D (25OHD) or alter inflammatory markers and lipids in overweight and obese youth. Further studie...

Eligibility Criteria

Inclusion

  • Ages 11 years to 17.99 years old
  • BMI: 85 percentile for age and gender

Exclusion

  • Patients who currently receive:
  • vitamin D supplementation \>= 400 IU/day
  • daily glucocorticoids or anti-epileptics
  • Patients who currently have or history of:
  • 25-OH vitamin D level \< 10 ng/ml or \> 60 ng/ml
  • rickets
  • diabetes mellitus
  • liver or kidney disease
  • malabsorptive disorders
  • genetic syndromes associated with obesity (i.e. Prader-Willi)
  • lactose deficiency or insufficiency
  • galactosemia

Key Trial Info

Start Date :

September 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01217840

Start Date

September 1 2010

End Date

August 1 2012

Last Update

November 29 2017

Active Locations (1)

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Stanford University School of Medicine

Stanford, California, United States, 94305