Status:

UNKNOWN

Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTs

Lead Sponsor:

KU Leuven

Conditions:

Neurofibromatosis Type 1

Eligibility:

All Genders

Brief Summary

Neurofibromatosis type 1 (NF1) is a frequent autosomal dominant disorder, caused by heterozygous mutations of the NF1 tumor suppressor gene (chr.17q11.2). One of the main clinical features is the deve...

Detailed Description

Introduction Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder occuring in 1 out of 3500 living newborns. The disease is caused by heterozygous mutations of the NF1 gene, located on chr...

Eligibility Criteria

Inclusion

  • according to NF1 criteria

Exclusion

  • NF1 patients where the tumor is already removed

Key Trial Info

Start Date :

October 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2011

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT01218152

Start Date

October 1 2010

End Date

December 1 2011

Last Update

October 11 2010

Active Locations (1)

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KULeuven/UZLeuven

Leuven, Vlaams-Brabant, Belgium, 3000