Status:
COMPLETED
Dopaminergic Modulation of Cognition and Psychomotor Function
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Dopamine Activity
Episodic Memory Consolidation
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
A recent study at our lab showed increased episodic memory consolidation and response readiness after treatment with methylphenidate in healthy volunteers. The investigators seek to replicate and exte...
Eligibility Criteria
Inclusion
- Male or female
- 18 to 45 years of age
- Healthy (i.e. absence of all exclusion criteria), normal static binocular acuity (corrected or uncorrected),
- Body mass index between 18.5 and 30
- Willingness to sign an informed consent.
Exclusion
- history of cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal, haematological or psychiatric illness.
- history of depression, bipolar disorder, anxiety disorder, panic disorder, psychosis, or attention deficit hyperactivity disorder will be excluded from participation.
- first-degree relative with a psychiatric disorder or a history with a psychiatric disorder
- excessive drinking (\>20 glasses of alcohol containing beverages a week
- pregnancy or lactation
- use of medication other than oral contraceptives
- use of recreational drugs from 2 weeks before until the end of the experiment
- any condition in which gastrointestinal motility might carry any risk
- any sensory or motor deficits which could reasonably be expected to affect test performance
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01218425
Start Date
November 1 2010
End Date
June 1 2012
Last Update
October 25 2012
Active Locations (1)
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1
Maastricht University
Maastricht, Limburg, Netherlands, 6200