Status:
UNKNOWN
The Neural Correlates of Food Choice Decision-making in Obesity and Weight Loss
Lead Sponsor:
The Miriam Hospital
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
California Institute of Technology
Conditions:
Obesity
Weight Loss
Eligibility:
FEMALE
35-55 years
Phase:
NA
Brief Summary
This study is designed to determine whether obese, normal weight, and successful weight loss maintainers differ in their food choice decision-making and/or executive function, and whether participatio...
Eligibility Criteria
Inclusion
- women, ages 35-55, who are either currently obese (BMI = 30-40 kg/m2), always normal weight (lifetime BMI \< 25, NW) or successful weight loss maintainers who have lost 10% of their body weight and maintained that loss for at least 1 year (lifetime maximum BMI = 30-40 kg/m2)
Exclusion
- weight loss medications, binge eating, standard MRI contraindications (e.g., metal implants, claustrophobia, pregnancy), left-handedness, food allergies, neurological or psychiatric conditions, including but not limited to schizophrenia, bipolar disorder, epilepsy, stroke and traumatic brain injury with loss of consciousness, and, among obese participants, inability to participate at two time points and lack of interest in participating in a behavioral weight loss trial
- serious current physical disease (e.g., heart disease and cancer) for which physician supervision of diet and exercise prescription is needed, physical problems that limit the ability to exercise, participation in a weight loss program in the last 2 months and intention to become pregnant in the next 6 months
Key Trial Info
Start Date :
March 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2016
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01218503
Start Date
March 1 2010
End Date
October 1 2016
Last Update
July 29 2013
Active Locations (2)
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1
Weight Control & Diabetes Research Center
Providence, Rhode Island, United States, 02903
2
Weight Control & Diabetes Research Center
Providence, Rhode Island, United States, 02903