Status:
COMPLETED
Evaluation of the Impact of Embryo Biopsy on the Reproductive Potential of Embryos Undergoing In Vitro Fertilization (IVF)
Lead Sponsor:
Reproductive Medicine Associates of New Jersey
Conditions:
Each Patient is Both Case and Control
1 Embryo Will be Biopsied and 1 Embryo is Not
Eligibility:
All Genders
18-35 years
Brief Summary
To assess the impact of embryo biopsy on the reproductive potential of human embryos.
Detailed Description
This study will recruit patients from the NY/NJ/CT/eastern PA area only. All patients will undergo an in vitro fertilization (IVF) cycle with hormonal stimulation and an egg retrieval procedure as de...
Eligibility Criteria
Inclusion
- This study will recruit patients from the NY/NJ/CT/eastern PA area only.
- Maximum of one prior failed IVF treatment cycle
- Female partner less than 35 years of age
- Normal day 3 FSH level (\<10 miu/mL)
- Total basal antral follicle count greater than or equal to 12
- Male partner with greater than 100,000 total motile spermatozoa and at least 1% normal forms
- Body mass index (BMI) \< or = 32
- Normal uterine cavity
Exclusion
- Diagnosis of chronic anovulation secondary to polycystic ovarian disease
- Diagnosis of endometrial insufficiency
- Clinical indication for pre-implantation genetic diagnosis (PGD) (undergoing IVF with PGD to rule out a known genetic defect)
- Use of testicular aspiration or biopsy procedures to obtain sperm
Key Trial Info
Start Date :
April 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01219504
Start Date
April 1 2008
End Date
September 1 2012
Last Update
January 23 2013
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Reproductive Medicine Associates of Connecticut
Norfolk, Connecticut, United States, 06850
2
Reproductive Medicine Associates of New Jersey
Morristown, New Jersey, United States, 07960
3
Reproductive Medicine Associates of New York
New York, New Jersey, United States, 10022