Status:
COMPLETED
Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
Ocean Spray Cranberries, Inc.
Conditions:
Urinary Tract Infection
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
The purpose of the research is to determine if eating sweetened, dried cranberries or strawberry fruit pieces will increase the types of different E. coli bacteria in the intestines which may reduce t...
Detailed Description
This is a research study about the number and types of bacteria that cause urinary tract infections (E. coli strains) that are present in the intestine. The bacteria will be collected and analyzed bef...
Eligibility Criteria
Inclusion
- Women, ages 18-65
- History of recurrent urinary tract infections defined as three in the past year, or two in the last six months
- Subjects must be willing to follow the study protocol that includes consuming the mandatory daily dose of cranberries or strawberry fruit pieces and traveling to the UWHC Urology clinic for scheduled rectal and vaginal swab procedures.
- The non-UTI-susceptible group will include women ages 18-65 with no history of recurrent UTI's as defined above.
Exclusion
- Women who:
- Are pregnant
- Have an immune compromising disease
- Have diabetes
- Have kidney stones
- Have chronic bowel inflammatory disease
- Have known allergies to cranberries, strawberries, elderberries, or wheat fiber
- Non-UTI-susceptible group will include women ages 18-65 with no history of recurrent UTI's as defined above.
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT01219595
Start Date
September 1 2010
End Date
September 1 2012
Last Update
January 29 2016
Active Locations (1)
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1
University of Wisconsin-Madison
Madison, Wisconsin, United States, 53792