Status:

COMPLETED

Comparison of AAIsafeR and DDD Modes in Non-selected Patients

Lead Sponsor:

Sorin Group Canada

Conditions:

Any Patient Who Fulfills the Inclusion Criteria to be Implanted With a Dual Chamber Pacemaker Maybe Included in the Study as Per ACC/AHA Guidelines

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

1 Purpose In patients with sinus node dysfunction (SND), the use of AAI mode is rare. In paroxysmal high-degree or complete atrio-ventricular (AV) block, paroxysmal vagally-mediated bradycardia, sing...

Detailed Description

In patients with sinus node dysfunction (SND), the use of AAI mode is rare. In paroxysmal high-degree or complete atrio-ventricular (AV) block, paroxysmal vagally-mediated bradycardia, single chamber ...

Eligibility Criteria

Inclusion

  • Inclusion criteria / Indications Any patient who fulfils one or more of the official guidelines to be implanted with a dual-chamber pacemaker (primo-implantation) may be included in the study.

Exclusion

  • Exclusion criteria / Contraindications
  • The patients presenting with one or more of the following characteristics cannot be included:
  • Permanent complete AV block
  • Permanent atrial and/or ventricular arrhythmias
  • already implanted with a cardioverter-defibrillator (ICD)
  • Likely to have a cardiac surgery in the next six months, mainly for:
  • severe coronary artery disease
  • severe valvular disease
  • Refuses to sign an consent form after having received the appropriate information
  • Refuses to co-operate
  • Not able to understand the study objectives and protocol
  • Not available for scheduled follow-up
  • With a life expectancy less than one year
  • Already included into another clinical study competing with the objectives of the CAN-SAVE R study.
  • \<18 years old.
  • Contraindications Any patient to whom a contraindication from device labeling applies shall not be included in the study.
  • \-

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2009

Estimated Enrollment :

450 Patients enrolled

Trial Details

Trial ID

NCT01219621

Start Date

April 1 2006

End Date

April 1 2009

Last Update

October 13 2010

Active Locations (10)

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Page 1 of 3 (10 locations)

1

Grey Nuns hospital

Edmonton, Alberta, Canada, T6L 5X8

2

Royal-Alex hospital

Edmonton, Alberta, Canada

3

Kingston General Hospital

Kingston, Ontario, Canada, K7L 2V7

4

Southlake hospital

Newmarket, Ontario, Canada