Status:
COMPLETED
Evaluation of Blood-retinal Barrier Functional Alterations by Optical Coherence Tomography
Lead Sponsor:
Association for Innovation and Biomedical Research on Light and Image
Collaborating Sponsors:
Fundação para a Ciência e a Tecnologia
Instituto Financeiro para o Desenvolvimento Regional
Conditions:
Diabetic Retinopathy
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to identify alterations of the blood-retinal barrier (BRB) in diabetic retinas using a novel non-invasive approach based on the Fourier domain high-definition optical cohe...
Detailed Description
Type 2 diabetic patients with nonproliferative diabetic retinopathy (NPDR) (study population) and healthy volunteers (control population). Inclusion Criteria: Age over 18 years; type-2 diabetes; NPD...
Eligibility Criteria
Inclusion
- Age over 18 years; type-2 diabetes; NPDR levels 10, 20 and 35/47 (ETDRS severity scale), and area of retinal leakage of at least 25% of the RLA map (macular area).
Exclusion
- Presence of media opacity; vitreous syneresis or posterior vitreous detachment, and; previous photocoagulation treatments or any type of intraocular surgery or intravitreal medications.
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01220804
Start Date
November 1 2010
End Date
March 1 2013
Last Update
April 25 2016
Active Locations (1)
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1
AIBILI
Coimbra, Portugal, 3000-548