Status:
COMPLETED
Influence of Tightly Glucose Control on Hyperglycemic Toxicity and Protein Catabolism in Critically Ill Patients
Lead Sponsor:
Kaohsiung Veterans General Hospital.
Conditions:
Critically Ill Patients
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
To compare the differences of urinary nitrogen excretion, nitrogen balance and clinical outcomes between tightly insulin therapy and conventional insulin therapy in the ICU.
Detailed Description
Critical illness is associated with increased circulating concentrations of proinflammatory cytokines, such as tumor necrosis factor (TNF-α), interleukin (IL)-1, and IL-6 which may be important mediat...
Eligibility Criteria
Inclusion
- Patients admitted to the adult ICU who had baseline blood glucose \> 180 mg/dl
- expected to require treatment in the ICU on 3 or more consecutive days.
Exclusion
- pregnant patients
- patients with chronic renal loss (Chronic renal loss was defined as persistent acute renal failure, complete loss of kidney function \> 4 weeks)
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
112 Patients enrolled
Trial Details
Trial ID
NCT01227148
Start Date
April 1 2006
End Date
December 1 2006
Last Update
October 25 2010
Active Locations (1)
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1
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan, 813