Status:

COMPLETED

Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products.

Lead Sponsor:

McNeil AB

Conditions:

Tobacco Dependence

Eligibility:

All Genders

19-50 years

Phase:

NA

Brief Summary

Comparative pharmacokinetic study of new oral nicotine replacement therapy products.

Detailed Description

This study compares new oral Nicotine Replacement Therapy (NRT) products containing 2 and 4 mg nicotine with NiQuitin™ lozenge 2 mg and 4 mg, after 12 hours of nicotine abstinence, with respect to nic...

Eligibility Criteria

Inclusion

  • Healthy subjects, smoking at least 10 cigarettes daily during at least one year preceding inclusion and BMI between 17.5 and 30.0 kg/m2.
  • Female participants of child-bearing potential are required to use a medically acceptable means of birth control.
  • A personally signed and dated informed consent document, indicating that the subject has been informed of all pertinent aspects of the study.

Exclusion

  • Pregnancy, lactation or intended pregnancy.
  • Treatment with an investigational product or donation or loss of blood within 3 month preceding the first dose of study medication.

Key Trial Info

Start Date :

August 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

104 Patients enrolled

Trial Details

Trial ID

NCT01227720

Start Date

August 1 2009

End Date

January 1 2010

Last Update

July 10 2012

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Lund University Hospital Clinical Trial Unit

Lund, Sweden, SE-221 85

2

McNeil AB Clinical Pharmacology R&D

Lund, Sweden, SE-222 20