Status:

COMPLETED

Clinical Efficacy of the Drug Ster® Compared With Predfort® in Control of Postoperative Inflammation in Cataract Surgery

Lead Sponsor:

Azidus Brasil

Conditions:

Inflammation

Cataract Surgery

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Is the primary objective of this investigation to compare the clinical efficacy of the drug test - Ster ® (prednisolone 1% ophthalmic suspension - Union Chemicals) in the comparator - Fort ® Pred (pre...

Detailed Description

The secondary objective is to compare the safety data observed during the study period, ie will be assessed the frequency and intensity of adverse reactions and compared statistically between groups.

Eligibility Criteria

Inclusion

  • Patients who agree with all study procedures and sign, by his own free will, IC;
  • Adult patients, regardless of gender, ethnicity or social status, with good mental health;
  • Patients who present at screening visit, a clinical diagnosis of cataract with an indication for corrective surgery with phacoemulsification technique.

Exclusion

  • Patients with a history or clinical diagnosis of other eye diseases such as glaucoma, corneal ulcers, scarring, and uveitis;
  • Patients with known hypersensitivity to any component of the drug under investigation;
  • Patients who have made use of systemic corticosteroids within 15 days before surgery;
  • Patients who have made use of topical corticosteroids in the 7 days before surgery;
  • Patients who have made use of systemic antibiotics in the 15 days preceding surgery;
  • Patients who have made use of topical antibiotics in the 7 days before surgery;
  • Patients presenting abnormality, at the discretion of the principal investigator in the following ophthalmic examinations Preoperative slit-lamp examination, measurement of intraocular pressure (applanation tonometry) and examination of background, other than the underlying disease (cataract);
  • Pregnant or lactating women.

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT01227876

Start Date

January 1 2011

End Date

August 1 2011

Last Update

November 2 2022

Active Locations (1)

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LAL Clínica Pesquisa e Desenvolvimento Ltda

Valinhos, São Paulo, Brazil