Status:

UNKNOWN

Influence of Oxidative Dysbalance on Secondary Osteoarthritis

Lead Sponsor:

Heinrich-Heine University, Duesseldorf

Conditions:

Osteoarthritis

Eligibility:

All Genders

18-70 years

Brief Summary

The important role of mechanical joint stress for the insert and progress of osteoarthritis (OA) is supported by recent studies. The degeneration of joint cartilage is caused either by unphysiological...

Detailed Description

Patients with clinically manifest OA typically consult the physician at time of irreversible cartilage destruction. This is due to the long time clinically silent progress of the disease. A biomarker ...

Eligibility Criteria

Inclusion

  • Planned knee joint arthroscopy
  • No history of trauma

Exclusion

  • Neoplasia
  • Rheumatoid arthritis
  • Intake of Steroids, cytostatic drugs,immunosuppression
  • Pregnancy or lactation
  • Addiction
  • Participation in other clinical trials

Key Trial Info

Start Date :

October 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2013

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT01228487

Start Date

October 1 2010

End Date

November 1 2013

Last Update

July 26 2011

Active Locations (1)

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1

Orthopedic Department, Heinrich-Heine University Medical School

Düsseldorf, North Rhine-Westphalia, Germany, D40225