Status:
SUSPENDED
Safe Use of Heparin Sodium in Patients With Chronic Renal Failure.
Lead Sponsor:
Azidus Brasil
Conditions:
Chronic Renal Failure
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The Heparin form a complex with a plasma protein, antithrombin III (ATIII), which is an endogenous anticoagulant. This complex inhibits the formation of thrombin and accelerates its destruction. Moreo...
Eligibility Criteria
Inclusion
- Adults of both sexes, regardless of color or social class;
- Age above 18 years;
- Patients who agree to participate in the study and signed the free and informed consent (attached);
- Insufficient patients in chronic renal dialysis scheme (3 times per week);
- Low Chronic Renal indication of anticoagulant during dialysis.
Exclusion
- Not agree to the terms described in informed consent;
- Patients with sensitivity to heparin sodium;
- Volunteer search with hypersensitivity to benzyl alcohol;
- Patients with a history of bleeding or change in blood clotting that can aggravate or terminate the clinical picture, such as tables of gastric ulcer;
- Patients with a history of peptic ulcer;
- Patients with cancer of any etiology, because of the possibility of compromising the function of the variable coagulation;
- Patients in a period of pregnancy and postpartum;
- Individuals with genetic abnormality of clotting system;
- Patients polytraumatized;
- Patients in use of glucocorticoids for at least 1 month;
- Patients in use of other anticoagulants;
- Patients with high rate of bleeding;
- Patients undergo any surgery performed less than 15 days because of the risk of the formation of hematomas at the site of surgery;
- Patients in use of drugs that affect the hemostasis;
- In addition to these, clinical characteristics that the medical criteria, can interfere with the study.
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2008
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01229072
Start Date
July 1 2008
End Date
July 1 2008
Last Update
November 3 2022
Active Locations (1)
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1
Lal Clinica Pesquisa E Desenvolvimento Ltda
Valinhos, São Paulo, Brazil, 13270000