Status:
COMPLETED
Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
1-18 years
Brief Summary
RATIONALE: Studying samples of tissue from patients with cancer the in laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research study is studying...
Detailed Description
OBJECTIVES: * To determine whether the pattern of global and TSG-specific promoter CpG island hypermethylation and gene silencing that we have shown characterizes MLL-rearranged (MLL-r) infant biline...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Available cryopreserved cells from diagnosis
- At least 2 x 10\^7 viably cryopreserved cells
- One of the following biologically defined cytogenetics/molecular cohorts:
- t(9;11)
- t(11;19)
- Other 11q23 translocations
- Normal cytogenetics
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT01229956
Start Date
November 1 2010
Last Update
May 19 2016
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