Status:
COMPLETED
Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway
Lead Sponsor:
University of Miami
Collaborating Sponsors:
GlaxoSmithKline
Conditions:
Asthma
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The addition of an inhaled long-acting beta-adrenergic agonist to an inhaled glucocorticosteroid improves disease control in persistent asthma. This observation has supported the use of long-acting be...
Detailed Description
Fourteen lifetime nonsmokers with a physician diagnosis of asthma will be recruited for the study. All subjects will be allowed to use short-acting beta-adrenergic agonists as rescue medication. Incl...
Eligibility Criteria
Inclusion
- Males and females, 18 to 65 years of age.
- FEV1 60-85% of predicted on the screening day. -
Exclusion
- 1\. Women of childbearing potential who do not use accepted birth control measures; pregnant and breast feeding women. 2. Cardiovascular disease and/or use of cardiovascular medications 3. Subjects with known beta-adrenergic agonist or glucocorticosteroid intolerance 4. Acute respiratory infection within four weeks prior to the study 5. Use, within two weeks prior to the study, of any anti-asthma medication not mentioned above
- \-
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01231230
Start Date
May 1 2007
End Date
August 1 2010
Last Update
June 30 2016
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