Status:
COMPLETED
Heart Rate Control With Esmolol in Septic Shock
Lead Sponsor:
Andrea Morelli
Conditions:
Septic Shock
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is investigate the effects on systemic hemodynamics and organ function of esmolol when used to maintain heart rate below a predefined threshold in patients with septic shock.
Detailed Description
154 septic shock patients with heart rate \> of 95 bpm and requiring vasopressor support to maintain mean arterial pressure between 65 and 75 mmHg despite adequate volume resuscitation, will be enroll...
Eligibility Criteria
Inclusion
- septic shock criteria
- presence of heart rate \> 95 bpm.
Exclusion
- Pregnancy
- age \< 18
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
154 Patients enrolled
Trial Details
Trial ID
NCT01231698
Start Date
December 1 2010
End Date
July 1 2012
Last Update
January 24 2013
Active Locations (1)
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1
Department of Anesthesiology and Intensive care of the University of Rome La Sapienza
Rome, Italy