Status:
UNKNOWN
The Neuroprotection of Remote Ischemic Preconditioning (RIPC) on Cardiac Surgery in Multicenter
Lead Sponsor:
Xijing Hospital
Conditions:
Cardiac Surgery Patients
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The current study is designed to clarify the neuroprotective effect of remote ischemic preconditioning on the patients underwent open-heart cardiac surgery.
Detailed Description
BACKGROUND: Brain ischemia and injury are commonly contributed to perioperative morbidity and mortality after cardiac surgery. Remote ischemic preconditioning (RIPC) is a phenomenon whereby brief peri...
Eligibility Criteria
Inclusion
- Patients diagnosed with acquired heart valve diseases scheduled for valve replacement or CABG
Exclusion
- Were unable to give informed consent
- Patients who presented with other systemic diseases such as hepatic,renal, and pulmonary diseases, or have had a heart operation before, were excluded.
- Additionally, patients taking antidiabetic sulfonylurea or glibenclamide were excluded because these agents have been shown to abrogate the cardioprotection elicited by ischemic preconditioning.
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2013
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01231789
Start Date
June 1 2009
End Date
August 1 2013
Last Update
August 21 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Xijing Hospital
Xi'an, Shaanxi, China, 710032