Status:

COMPLETED

Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies.

Lead Sponsor:

University Hospital, Caen

Conditions:

Cirrhosis

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The project will improve scientific knowledge regarding a recent law applying potentially to every french driver. It will give for the first time an indication on the impact of alerting treatments on ...

Detailed Description

Excessive daytime sleepiness is responsible of 20% of traffic accidents and 2/3 of truck accidents on French Freeways. Since the publication of a new law (2005 december 28th - Official Journal) regula...

Eligibility Criteria

Inclusion

  • Cirrhosis proved by histologic or clinico-biologics criteria, whatever its severity, its stability defined by a child stable score (variation \< 2 points for the last month) without any other disease which could be responsible of excessive daytime sleepiness
  • driver's licence since at least 2 years
  • driving more than 2000 Km/year
  • registered to French national health and pensions organization
  • having given their written light agreement in order to participate in the study.

Exclusion

  • Night workers
  • neurologic disease
  • recent strong complication (\< 30 days)
  • recent antibiotics or lactulose intake
  • substance abusers (alcohol)
  • hepatoma more than 5 cm
  • disorder associated which engaged life prognostic in a short time
  • glycemia fasted \> 8 mmol/l
  • haemoglobin \< 10g/l
  • neurologic or psychiatric disorders associated which affect superiors functions,
  • hepatic encephalopathy stage 3 or 4
  • having participated in a clinical study during the last 6 months
  • drugs abusers
  • unable to drive.

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT01231828

Start Date

September 1 2009

End Date

December 1 2012

Last Update

February 27 2013

Active Locations (1)

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1

University Hospital of Caen

Caen, France, 14033