Status:
COMPLETED
Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
Lead Sponsor:
Prince of Songkla University
Conditions:
Pruritus
Eligibility:
All Genders
15-70 years
Phase:
NA
Brief Summary
Intrathecal morphine provides good postoperative analgesia for up to 18-24 hour after administration. Pruritus is the most common side effect of intrathecal morphine, which the incidence was reported ...
Detailed Description
The study was approved by the ethic committee of Songklanagarind Hospital in Songkhla, Thailand, and was designed as a randomized, double-blind, placebo-controlled trial. All patients gave their infor...
Eligibility Criteria
Inclusion
- aged between 15-70 yr, ASA physical status I-III, and were scheduled for lower limb surgery under spinal anesthesia.
Exclusion
- contraindication for spinal anesthesia, known allergy history to gabapentin, complaint of pruritus before surgery, morbid obesity (BMI \> 35), coexisting skin disorder, and any systemic disease associated with pruritus. Patients who had history of seizure attacks, mental illness, chronic headache, or neuropathic pain and were concomitantly using of anticonvulsants, antidepressants, antipsychotics, or antihistamine
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT01236859
Start Date
September 1 2009
End Date
November 1 2010
Last Update
October 9 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Songklanagarind Hospital
Hat Yai, Changwat Songkhla, Thailand, 90110