Status:
UNKNOWN
Development of A Technique to Predict Antidepressant Responsiveness in Depressive Patients
Lead Sponsor:
Samsung Medical Center
Conditions:
Depression
Continuous Antidepressant Abuse
Eligibility:
All Genders
19-89 years
Phase:
NA
Brief Summary
First, the investigators examined the functional relevance of serotonin transporter polymorphisms by quantifying the activity of serotonin transporter in blood platelets of genotyped healthy volunteer...
Detailed Description
The purpose of this study is 1. to determine whether serotonin transporter genotypic or functional differences between depressive patients and normal controls were existed. 2. to determine the relati...
Eligibility Criteria
Inclusion
- Eligible patients were enrolled in the clinical trials program of hte Samsung Medical Center Geropsychiatry and Affective Disorder Clinics(Seoul, Korea). They received a semistructured diagnostic interview, the Samsung Psychiatric Evaluation Schedule. The affective disorder section of the Samsung Psychiatric Evaluation Schedule uses the Korean version of the structured clinical interview for the diagnostic and statistical manual of mental disorders, Fourth edition.
- interview with one more patient's family member for objective diagnosis and final diagnosis decision by agreements of two more psychiatric physicians
Exclusion
- received psychotropic medication within 2 weeks of the study or fluoxetine within 4 weeks
- potential study participants for pregnancy, significant medical conditions, abnormal laboratory baseline values, unstable psychiatric features(eg.suicidal), history of alcohol of drug dependence, seizures, head trauma with loss of consciousness, neurological illness, or concomitant Axis I psychiatric disorder.
Key Trial Info
Start Date :
October 1 1999
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2016
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01237275
Start Date
October 1 1999
End Date
December 1 2016
Last Update
December 31 2015
Active Locations (1)
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1
Samsung Medical Center
Kangnam, Seoul, South Korea