Status:
COMPLETED
Importance of Liver Innervation for the Osmopressor Response in Humans
Lead Sponsor:
Hannover Medical School
Conditions:
PHYSIOLOGICAL PHENOMENA
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
In patients with autonomic dysfunction water drinking elicits a pressor response mediated by sympathetic activation. If any, in healthy subjects there is only a slight increase in blood pressure. Howe...
Eligibility Criteria
Inclusion
- 3 to 24 month past liver or kidney transplantation
- age 18 to 60
- written informed consent
- ability to understand the oral and written information
Exclusion
- pregnancy or lactation
- transplantation of another organ
- chronic heart or vascular disease
- known alcohol or drug abuse
- psychiatric diseases (e.g. chronic depression, schizophrenia, drug addiction)
Key Trial Info
Start Date :
November 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2011
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01237431
Start Date
November 1 2009
End Date
January 1 2011
Last Update
February 23 2011
Active Locations (1)
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1
Hannover Medical School
Hanover, NDS, Germany, 30625