Status:

COMPLETED

Physiotulle vs Urgotul in the Treatment of Leg Ulcer

Lead Sponsor:

Coloplast A/S

Conditions:

Leg Ulcers

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The aim of this study is to assess the pain at removal of Physiotulle dressing in comparison with that of Urgotul dressing in patients presenting a venous (or predominantly) venous leg ulcer.

Eligibility Criteria

Inclusion

  • Patient of either sex over 18 who have not been declared legally incompetent and who having given his written informed consent
  • Patient with venous or predominantly venous leg ulcer (ankle-brachial index \> 0.8)
  • Patient with venous or predominantly venous leg ulcer in granulation phase (granulation tissue \> 70 %)
  • Patient with venous or predominantly venous leg ulcer with low exsudate
  • Patient with venous or predominantly venous leg ulcer with a wound surface between 4 cm² and 170 cm²
  • Patient with venous or predominantly venous leg ulcer that has been treated with an appropriate compression in the two weeks prior to inclusion
  • Patient available to be monitored for at least 4 weeks
  • Patient able to answer questionnaires and particularly to evaluate his pain

Exclusion

  • Patient whose leg ulcer is locally infected (At least 3 of 5 clinical signs suggestive of infection \*)\* 5 signs suggestive of infection: pain, exsudate, smell, oedema, erythema
  • Patient requiring an analgesic treatment for the care (before dressing removal)
  • Patient whose ulcer belongs to angiodermatitis type or demonstrates a vasculitis
  • Patient with arterial ulcer
  • Patient with purely traumatic, infectious or neoplastic origin ulcer
  • Patient with a diabetic neuropathy of lower limbs
  • Patient with a known allergy to one of Physiotulle or Urgotul components
  • Patient already participating in another clinical study
  • Pregnant or breastfeeding patient
  • Patient who have been taking corticoids \> 10mg / day or cytostatics by systematic way for the three months prior to inclusion
  • Patient who have undergone surgery of saphenous trunk in the two months prior to inclusion

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2011

Estimated Enrollment :

188 Patients enrolled

Trial Details

Trial ID

NCT01238419

Start Date

November 1 2009

End Date

May 1 2011

Last Update

September 5 2011

Active Locations (34)

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Page 1 of 9 (34 locations)

1

Bispebjerg ^Hospital

Bispebjerg, NV, Denmark, 2400

2

Arhus Sygehus

Aarhus, Denmark, 8000

3

Odense Universitets Hospital

Odense, Denmark, 5000

4

Cabilet Medical

Abbeville, France, 80100

Physiotulle vs Urgotul in the Treatment of Leg Ulcer | DecenTrialz