Status:
COMPLETED
Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Lead Sponsor:
University of Missouri, Kansas City
Collaborating Sponsors:
United States Department of Defense
Conditions:
Hemorrhagic Shock
Eligibility:
All Genders
21-65 years
Phase:
NA
Brief Summary
Overall aim of this work is to evaluate new methods of resuscitation that can be applied by front-line responders on the battlefield, in civilian life, or which can be used during initial resuscitatio...
Detailed Description
Shock is a leading cause of death among American forces in battle, with many trauma victims dying of early hemorrhagic shock or from late septic shock.1 Shock is defined as circulatory collapse, when ...
Eligibility Criteria
Inclusion
- Blunt or penetrating trauma patients who meet Truman Medical Center criteria for a trauma activation.
- These patients will typically be in shock and have blunt injuries or penetrating trauma.
- Patients must be alert, awake, oriented, and responsive and be English speaking males or females between the ages 21-65.
Exclusion
- traumatic cardiac arrest patients,
- pregnant patients,
- interhospital transfer patients,
- non-English speaking patients,
- patients with suspected or confirmed Human Immunodeficiency Virus (HIV) or AIDs based on clear history,
- prior laboratory tests, or strong clinical suspicion; patients with clinical evidence of impaired mental function;
- patients with continuing hypotension or tachycardia after resuscitation;
- patients with blood alcohol in excess of 80mg/dl;
- signs suggestive of coagulopathy;
- allergy to glutamine;
- liver disease or renal disease.
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT01239680
Start Date
January 1 2011
End Date
December 1 2013
Last Update
June 17 2014
Active Locations (2)
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1
Truman Medical Center-Hospital Hill
Kansas City, Missouri, United States, 64108
2
Univeristy of Missouri-Kansas City
Kansas City, Missouri, United States, 64108