Status:

TERMINATED

Aromasin® As Adjuvant Treatment In Postmenopausal Women With Invasive, Estrogen Receptor Positive Early Breast Cancer

Lead Sponsor:

Pfizer

Conditions:

Breast Neoplasms

Eligibility:

FEMALE

Brief Summary

This non-interventional study will be conducted in several Eastern European countries to assess the safety, tolerability and efficacy of Aromasin® when it is administered in real-word setting in postm...

Detailed Description

The study prematurely discontinued on October 11, 2011 due to slow enrollment. It should be noted that safety concerns have not been seen in this study and have not factored into this decision.

Eligibility Criteria

Inclusion

  • Postmenopausal females, defined as one from the next :
  • Natural menopause ≥1 year,
  • Surgical ovariectomy,
  • Chemotherapy-induced amenorrhoea ≥ 2 years.
  • Patients who have had surgical treatment for histologically confirmed breast cancer that was non-metastatic at the time of the initial diagnosis.
  • Patients who are disease-free after 2 to 3 years of adjuvant tamoxifen treatment.
  • Patients whose tumour was estrogen receptor positive (ER+).
  • Evidence of a personally signed and dated informed consent document indicating that the subject (or a legally acceptable representative) has been informed of all pertinent aspects of the study.

Exclusion

  • Patients for whom Aromasin® treatment is contraindicated (see SmPC).
  • Metastatic breast cancer or a contra lateral tumour.
  • Other concomitant adjuvant endocrine therapy.
  • Other concomitant antineoplastic treatment.
  • Participation in a clinical trial with an investigational drug during the 30 days prior to enrolment in the study.

Key Trial Info

Start Date :

April 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2011

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT01239745

Start Date

April 1 2011

End Date

October 1 2011

Last Update

October 31 2012

Active Locations (11)

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Page 1 of 3 (11 locations)

1

General Hospital Karlovac

Karlovac, Croatia, 47000

2

University Hospital Center Osijek

Osijek, Croatia, 31000

3

General Hospital Pula

Pula, Croatia, 52000

4

University Hospital Center Rijeka

Rijeka, Croatia, 51000