Status:

COMPLETED

Platform Exercise Training

Lead Sponsor:

University of Iowa

Conditions:

Knee Osteoarthritis

Eligibility:

FEMALE

45-60 years

Phase:

NA

Brief Summary

The purpose of this randomized, controlled trial is to determine whether a vibration platform exercise program will be more effective than a standard platform exercise program in improving quadriceps ...

Detailed Description

Osteoarthritis (OA) is the most common disabling disease in older adults,(1) affecting over 25 million Americans, resulting in significantly impaired function and mobility(2) and a societal economic b...

Eligibility Criteria

Inclusion

  • age 45-60
  • female
  • history of knee injury or surgery (except replacement surgery) or body mass index (BMI) greater than or equal to 25.

Exclusion

  • diagnosis of knee osteoarthritis
  • inflammatory arthritis such as rheumatoid or psoriatic arthritis
  • knee replacement
  • metallic implant or stent placement surgery or any implanted devices
  • surgery or lower limb injury in the last 6 months that affects walking ability
  • lower limb amputation (other than single ray)
  • unable to walk without an assistive device
  • wounds that contraindicate weight-bearing exercise
  • acute infection or inflammation that contraindicates exercise
  • acute disk related problems (new lower back pain in the last 3 months or severe enough to affect walking)
  • osteonecrosis
  • currently pregnant or planning to become pregnant
  • kidney, bladder or gallstones that have not been passed
  • retinal detachment
  • ever experienced deep vein thrombosis
  • type 1 diabetes mellitus (insulin dependent)
  • history of myocardial infarction or stroke in the last year
  • medical conditions that affect walking ability or ability to take part in the study or exercise such as; Alzheimer's disease, multiple sclerosis, Parkinson's disease, severe cardiovascular disease, congestive heart failure, severe emphysema, severe asthma, severe dysrhythmias or pacemaker
  • Any type of implanted pump (e.g. Morphine, baclofen) or catheter (e.g. In kidney, brain or spine)
  • neuropathy (by Semmes-Weinstein Monofilament)
  • uncontrolled epilepsy
  • active cancer (\< 5 years since remission) or other illness expected to be terminal within 1 year
  • concurrent participation in another research study
  • Inability to follow protocol (e.g. lack of ability to attend visits or understand instructions)
  • frequent knee pain on most of the last 30 days

Key Trial Info

Start Date :

November 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2011

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT01239823

Start Date

November 1 2010

End Date

March 1 2011

Last Update

April 11 2011

Active Locations (1)

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1

The University of Iowa

Iowa City, Iowa, United States, 52242