Status:
COMPLETED
Effectiveness of Theta-burst Stimulation (TBS) in Patients With Major Depression
Lead Sponsor:
University of Regensburg
Conditions:
Depression
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Repetitive Transcranial Magnetic Stimulation (rTMS) as well as Theta- Burst Stimulation of the frontal cortex are used to modulate the neuronal excitability in patients with depression. In the propose...
Detailed Description
Depression is a common mental disorder that presents with depressed mood, loss of interest, feelings of guilt or low self-worth, disturbed sleep or appetite, low energy, and poor concentration. These ...
Eligibility Criteria
Inclusion
- Episode of depression (unipolar or bipolar)( ICD-10)
- Female or male between 18 and 70 years
- Skills to participate in all study procedures
- 18 or more points in the Hamiliton rating scale or depression
- Stable antidepressant drugs
- Written informed consent
Exclusion
- Clinically relevant unstable internal or neurological comorbidity
- Evidence of significant brain malformations or neoplasm, head injury
- Cerebral vascular events
- Neurodegenerative disorders affecting the brain or prior brain surgery
- Metal objects in and around body that can not be removed
- Pregnancy
- Alcohol or drug abuse
- Epilepsy or a pathological EEG
- Heart pacemaker
- High dose tranquillizers
Key Trial Info
Start Date :
April 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT01240083
Start Date
April 1 2010
End Date
October 1 2011
Last Update
October 16 2013
Active Locations (1)
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1
University of Regensburg- Dept of Psychiatry
Regensburg, Bavaria, Germany, 93053