Status:
COMPLETED
FLT-PET Imaging of Brain Tumors in Children
Lead Sponsor:
Frederick Daniel Grant
Collaborating Sponsors:
Dana-Farber Cancer Institute
Conditions:
Brain Neoplasms
Eligibility:
All Genders
Up to 21 years
Phase:
PHASE2
Brief Summary
Brain tumors are the leading cause of death from solid tumors in children. Tumor imaging is important in the management of these tumors, but current imaging methods have limitations in providing the n...
Detailed Description
Although pediatric central nervous system tumors are rare, they are a significant contributor to morbidity and mortality in children. Tumor staging, detecting recurrent tumor, and assessing the respon...
Eligibility Criteria
Inclusion
- age 21 years or less
- capable of achieving imaging without need for sedation or anesthesia (typically age 8 years or greater, but there is no lower limit for age for eligibility)
- Karnofsky Performance Status of 50 or greater in subjects age 12 years or greater, for age less than 12 years a Lansky play scale of 50% or greater
- Patients receiving steroids and/or anti-seizure medications are eligible
Exclusion
- clinically active infection
- pregnancy or breast-feeding
- serious intercurrent medical illness
- require emergency surgical intervention that would be inappropriately delayed by FLT-PET imaging
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 5 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01244737
Start Date
October 1 2010
End Date
February 5 2023
Last Update
July 11 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Children's Hospital, Boston
Boston, Massachusetts, United States, 02115