Status:
COMPLETED
Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Severe Periodontitis
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
Parodontitis Aggressive
Parodontitis Chronic
Eligibility:
MALE
12+ years
Phase:
NA
Brief Summary
The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses. However it is thought...
Eligibility Criteria
Inclusion
- Men exclusively
- 12 years minimum
- 2 patients affected by chronic periodontitis
- 2 patients affected by aggressive periodontitis
- 2 healthy patients (orthodontics extraction)
- Subject who have read and understood the information note relative under investigation and who have signed the informed consent
- Subject whose legal representative signed the parental consent (if minor patient)
Exclusion
- Patient with contre-indication to dental extraction
- Patient witn serious blood disease
- Patient who exhibits systemic condition incompatible with the realization of the study
- Patient treated with oral retinoids, bisphosphonates, oral anticoagulants and anticonvulsivants
- Patient who presents za buccal carcinoma treated with radiotherapy
- Patient who have received during the past 6 months: anti-inflammatory drugs, anti-cancerous or immunosuppressive chemiotherapy
- Patient who presents a linguistic or psychic incapacity to understand information
- Female patient
Key Trial Info
Start Date :
January 17 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT01246648
Start Date
January 17 2011
End Date
April 1 2015
Last Update
June 27 2024
Active Locations (1)
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1
CHU de Nice, Hôpital Saint Roch
Nice, France, 06000