Status:
COMPLETED
Vitamin D and the Health of Blood Vessels in Kidney Disease
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
The Kidney Foundation of Canada
Pfizer
Conditions:
Chronic Kidney Disease (CKD)
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Individuals with kidney disease have a high risk of heart disease. This is not related to traditional risk factors, such as high blood pressure, high cholesterol or being overweight. A lack of vitamin...
Detailed Description
Most people living in Canada do not receive enough vitamin D from the sun or from the food they eat. When a person has kidney disease this is a particular problem as kidney disease stops what little v...
Eligibility Criteria
Inclusion
- patients with an estimated glomerular filtration rate (eGFR) between 15 - 45 ml/min, and \<2ml/min change in glomerular filtration rate (GFR) over the past 6 months
- treated with maximal conventional cardiovascular disease (CVD) risk reduction medications
Exclusion
- patients with estimated glomerular filtration rate (eGFR) change of \>2.1 ml/min over the past 6 months
- those who have terminal malignancies
- those with planned transplant within 6 months, or who are likely to commence renal replacement therapy (dialysis) within the 6 months after enrolment
- those with active infections or active inflammatory diseases (Systemic Lupus Erythematosus (SLE), vasculitis)
- those who refuse to give informed consent
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
129 Patients enrolled
Trial Details
Trial ID
NCT01247311
Start Date
November 1 2010
End Date
August 1 2014
Last Update
June 15 2017
Active Locations (1)
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1
St Paul's Hospital & Vancouver General Hospital
Vancouver, British Columbia, Canada