Status:
TERMINATED
Comparative Effects on Diaphragmatic Electrical Activity and Respiratory Pattern of Various Levels of Assistance
Lead Sponsor:
Prof. Philippe Jolliet
Collaborating Sponsors:
University of Lausanne Hospitals
Conditions:
Respiratory Failure
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Exploration of the effects on diaphragmatic electrical activity (EMG) and on respiratory pattern of various level of assistance delivered by the ventilator in intubated spontaneously breathing patient...
Detailed Description
Exploration of the effects on diaphragmatic electrical activity (EMG) and on respiratory pattern of various level of assistance delivered by the ventilator in intubated spontaneously breathing patient...
Eligibility Criteria
Inclusion
- \- Patients admitted to the ICU, intubated for acute respiratory failure, and ventilated in PS mode will be eligible for inclusion in the study.
Exclusion
- Severe hypoxemia requiring an FIO2 \> 0.5
- hemodynamic instability (defined as the need for high doses of catecholamines namely ≥ 0.5 μg/kg min- and/or high need in volume resuscitation namely more than two litres of crystalloids in two hours-)
- oesophageal problem such as hiatal hernia, oesophageal varicosities, oesophageal surgery;
- active upper gastro-intestinal bleeding;
- known coagulation disorder;
- any other contraindication to the insertion of a naso-gastric tube;
- poor short term prognosis (death expected within the next seven days)
- age \< 18 years old.
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT01248845
Start Date
August 1 2010
End Date
June 1 2016
Last Update
May 8 2017
Active Locations (1)
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1
CHUV, University hospital of lausanne
Lausanne, Switzerland, 1011