Status:

COMPLETED

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

Lead Sponsor:

Massachusetts Eye and Ear Infirmary

Collaborating Sponsors:

University of Iowa

Alcon Research

Conditions:

Myopia

Refractive Error

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.

Detailed Description

An estimated 40 million people in the United States wear contact lenses, with approximately 38 million soft lens wearers and 2 million rigid gas permeable lens wearers. The ocular surface has been sho...

Eligibility Criteria

Inclusion

  • Subjects must be 18 years of age and may be of any race and either gender.
  • Subjects must not have ever worn contact lenses.
  • Subjects must have normal, healthy eyes.

Exclusion

  • Subjects must not use additional lens cleaners.
  • subjects must not have any ocular or systemic disease.
  • Subjects must not have history of ocular surgery/trauma within the last 6 months.

Key Trial Info

Start Date :

August 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2012

Estimated Enrollment :

94 Patients enrolled

Trial Details

Trial ID

NCT01250925

Start Date

August 1 2010

End Date

July 1 2012

Last Update

January 10 2017

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Iowa

Iowa City, Iowa, United States, 52242-1091

2

Massachusetts Eye and Ear Infirmary

Boston, Massachusetts, United States, 02114

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