Status:
COMPLETED
Non-surgical Periodontal Therapy Effects Metabolic Control in Diabetics
Lead Sponsor:
Mashhad University of Medical Sciences
Conditions:
Metabolic Control
Eligibility:
All Genders
30-70 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether nonsurgical periodontal therapy is effective in the metabolic control of patients with type II Diabetes mellitus.
Detailed Description
Type 2 diabetes mellitus (DM2), the most common type of diabetes, is characterized by hyperglycemia, hyperlipidemia, and associated complications. The classic major complications of diabetes are micro...
Eligibility Criteria
Inclusion
- (1) mild to moderate periodontitis according to the criteria of the American Academy of Periodontology (32); (2) diagnosis of DM2 with glycated hemoglobin (HbA1c) values over 7%; (3) no major diabetic complications; (4) blood sugar controlled with glybenclamide and metformin, without insulin administration; and (5) no systemic antibiotic administration or periodontal treatment within the last 6 months.
Exclusion
- (1) presence of systemic diseases other than DM2 that may influence the course of periodontal disease; (2) intake of immunosuppressive drugs, steroids, hydantoin, or non-steroidal anti-inflammatory drugs; (3) tobacco use; (4) pregnancy or intention to become pregnant during the study period; (5) fixed orthodontic appliances; and (5) refusal or inability to give informed consent
Key Trial Info
Start Date :
June 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01252082
Start Date
June 1 2007
End Date
September 1 2008
Last Update
April 8 2015
Active Locations (1)
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1
Mashhad Dental School, Mashhad University of Medical Sciences
Mashhad, Khorasan Razavi, Iran, 91735-984