Status:

COMPLETED

A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis

Lead Sponsor:

Intersect ENT

Conditions:

Chronic Sinusitis

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to assess the safety and efficacy of the Propel mometasone furoate implant when used following Functional Endoscopic Sinus Surgery (FESS) in patients with Chronic Sinusiti...

Detailed Description

The purpose of this study is to assess the safety and efficacy of the Propel mometasone furoate implant when used following Functional Endoscopic Sinus Surgery (FESS) in patients with Chronic Sinusiti...

Eligibility Criteria

Inclusion

  • Patient has bilateral chronic sinusitis confirmed by CT scan and defined as inflammation of the mucosa of the nose and paranasal sinuses of at least 8 consecutive weeks' duration.
  • Patient is indicated for and has consented to FESS.
  • FESS successfully completed without significant complication that in the opinion of the physician would confound study results and the patient's anatomy remains amenable to Sinus Stent placement.
  • CT Imaging
  • CS diagnosis confirmed and documented by CT Scan within 6 months of the procedure.
  • Patient has minimum total CT score (Lund-Mackay method) of 6. • Patient has bilateral ethmoid sinus disease confirmed by CT.

Exclusion

  • insulin dependent diabetics
  • oral steroid dependent condition
  • glaucoma, ocular hypertension, posterior subcapsular cataracts
  • middle turbinate resection

Key Trial Info

Start Date :

December 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

105 Patients enrolled

Trial Details

Trial ID

NCT01253577

Start Date

December 1 2009

End Date

October 1 2010

Last Update

June 22 2015

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Central California ENT

Fresno, California, United States, 93720

2

Colorado ENT & Allergy

Colorado Springs, Colorado, United States, 80909

3

Northwestern University

Chicago, Illinois, United States, 60611

4

Northshore University Health System

Evanston, Illinois, United States, 60201