Status:
COMPLETED
Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in Children
Lead Sponsor:
University of Cape Town
Conditions:
Kerosene Pneumonitis
Eligibility:
All Genders
3-13 years
Phase:
NA
Brief Summary
Paraffin (kerosene) ingestion in the developing world accounts for a large number of visits to healthcare facilities, especially amongst children. There is no evidence in animals and no good evidence ...
Detailed Description
The average of 100 children per annum attending Red Cross War Memorial Children's Hospital 9RCWMCH) with the diagnosis of kerosene ingestion would give a sample of 200 children over a two-year period,...
Eligibility Criteria
Inclusion
- Ingestion in the preceding 24 hours
- Presence of respiratory symptoms and/or signs at presentation
- Informed consent obtained from parent or legal guardian
- Resident within the Red Cross Hospital drainage area and able to come for two follow-up appointments
Exclusion
- Asymptomatic and no clinical signs
- Too ill to be excluded from receiving an antibiotic as judged by:
- Requiring more than 2L/min nasal-prong oxygen
- Requiring continuous or intermittent positive airway pressure ventilation
- Fever \> 40˚C
- Needing an antibiotic for another reason e.g. otitis media, tonsillitis
- Current antibiotic use, prior to kerosene ingestion
- Allergic to amoxicillin
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT01253980
Start Date
July 1 2010
End Date
September 1 2011
Last Update
November 9 2015
Active Locations (1)
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1
Red Cross War Memorial Children's Hospital
Cape Town, Western Cape, South Africa, 7700