Status:
COMPLETED
Probiotics in Primary Care
Lead Sponsor:
Milton S. Hershey Medical Center
Conditions:
Antibiotic Side Effect
Eligibility:
All Genders
18-79 years
Phase:
NA
Brief Summary
Antibiotics are lifesaving medicines and generally safe, yet unwanted side effects are common. While destroying illness-causing 'bad' bacteria, antibiotics can upset the protective 'good' bacteria in ...
Detailed Description
Objectives Several studies have demonstrated that probiotics can be helpful in preventing antibiotic-associated diarrhoea in hospitalized patients. However, the extent to which probiotics may benefit ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- adults 18 - 79 years of age with infection requiring an oral antibiotic.
- Must be able to be contacted via telephone.
- Exclusion criteria:
- pregnancy,
- breast-feeding,
- those receiving tube feeding,
- those with diarrhea as a current symptom of present illness, and pre-existing illnesses that contribute to diarrhea such as inflammatory bowel disease,
- irritable bowel syndrome, colitis or celiac disease.
- Those undergoing active cancer treatments with chemotherapeutic or radiation therapy,
- immunocompromised persons,
- history of cardiac valvular disease,
- those taking a laxative or stool softener on a daily basis, as well as
- persons treated with an antibiotic in the previous 60 days,
- new antibiotic prescription that exceeds a 10 day course, or regular use of a probiotic within the previous three weeks (including daily ingestion of yogurt).
Exclusion
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT01254097
Start Date
March 1 2011
End Date
April 1 2014
Last Update
September 25 2015
Active Locations (1)
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1
M.S. Hershey Medical Center, Dept of Family and Community Medicine
Hershey, Pennsylvania, United States, 17033