Status:

COMPLETED

Evaluating Preventive Therapy With Oint Threolone, Synthomycine or Aqua Cream, for EGFR'I Induced Acneiform Rash

Lead Sponsor:

Rabin Medical Center

Conditions:

Acneiform Rash

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The investigators hypothesized that topical anti-inflammatory treatment could counteract the inflammatory reaction induced by EGFR'Is.

Detailed Description

The investigators hypothesized that topical anti-inflammatory treatment could counteract the inflammatory reaction induced by EGFR'Is.

Eligibility Criteria

Inclusion

  • Patients who are planed to initiate treatment with either cetuximab , erlotinib, gefitinib or panitumumab.

Exclusion

  • Patients who received any facial topical treatment / systemic antibiotics or any anti-inflammatory drug during the 2 weeks prior to study initiation.
  • Known hypersensitivity to ointment Synthomycine or to Threolone.
  • Patients presented with cutaneous rash during the 2 weeks prior to study initiation

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2017

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT01256437

Start Date

January 1 2011

End Date

March 1 2017

Last Update

May 9 2017

Active Locations (1)

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1

Davidoff Center, Rabin Medical Center, Beilinson

Petah Tikva, Israel, Israel, 49100