Status:
TERMINATED
Environmental and Genetic Determinants of NPC
Lead Sponsor:
National Cancer Institute (NCI)
Collaborating Sponsors:
Academia Sinica, Taiwan
National Taiwan University Hospital
Conditions:
Nasopharyngeal Neoplasms
Herpesvirus 4, Human
Eligibility:
All Genders
21-100 years
Brief Summary
Background: \- Nasopharyngeal carcinoma (NPC) a common malignant tumor in southern China and Southeast Asia. Infection with Epstein-Barr virus is believed to be necessary for the development of NPC; ...
Detailed Description
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in southern China and Southeast Asia. While infection with Epstein-Barr Virus (EBV) is believed to be necessary for the develo...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Eligibility criteria for cases:
- Incident diagnosis of NPC between 2010-2015
- Age greater than or equal to 21 years at NPC diagnosis
- Histologically confirmed
- Resident of northern Taiwan greater than or equal to 6 months
- Eligibility criteria for controls:
- Resident of northern Taiwan greater than or equal to 6 months
- Matched to case based on age at diagnosis, gender, and ethnicity
- EXCLUSION CRITERIA:
- Exclusion criteria for controls:
- \- Clinic attendance due to conditions associated with EBV or smoking
Exclusion
Key Trial Info
Start Date :
December 8 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 2 2020
Estimated Enrollment :
3500 Patients enrolled
Trial Details
Trial ID
NCT01257100
Start Date
December 8 2010
End Date
June 2 2020
Last Update
June 4 2020
Active Locations (6)
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1
Academia Sinica 128 Academia Road
Taipei, Taiwan
2
Cathay General Hospital 280 Renai Rd, Section 4
Taipei, Taiwan
3
Far Easter Memorial Hospital 21, NanYa S. Rd, Section 2, Ban-Chiao
Taipei, Taiwan
4
Koo Foundation Sun Yat-Sen Cancer Center
Taipei, Taiwan