Status:

COMPLETED

Safety and Efficacy of Galvus in Elderly Type 2 Diabetes Patients

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

70+ years

Phase:

PHASE3

Brief Summary

This study will evaluate the efficacy and safety of vildagliptin 50 mg bid in elderly patients with Type 2 Diabetes Mellitus (T2DM).

Eligibility Criteria

Inclusion

  • age: ≥ 70 years inclusive at Visit 1.
  • patients with a confirmed diagnosis of T2DM
  • HbA1c of ≥ 7% and ≤10.0% by central laboratory at Visit 1 and assessed by the investigator to be inadequately controlled
  • body mass index (BMI) in the range of 19-45kg/m2

Exclusion

  • FPG ≥ 270 mg/dL (≥ 15.0 mmol/L)
  • previous or current participation in any vildagliptin clinical study.
  • history of hypersensitivity to DPP-4 inhibitors.
  • concurrent medical condition that may interfere with the interpretation of efficacy and safety data during the study.
  • donation of blood or significant blood loss equaling to at least one unit of blood within the past 2 weeks of start of study or a blood transfusion within the past 12 weeks or planned regular transfusions during the study period Other protocol-defined inclusion/exclusion criteria may apply

Key Trial Info

Start Date :

December 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2012

Estimated Enrollment :

431 Patients enrolled

Trial Details

Trial ID

NCT01257451

Start Date

December 1 2010

End Date

March 1 2012

Last Update

December 18 2012

Active Locations (46)

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Page 1 of 12 (46 locations)

1

Novartis Investigative Site

Wichelen, Belgium, Belgium, 9260

2

Novartis Investigative Site

Buizingen, Belgium, 1501

3

Novartis Investigative Site

De Pinte, Belgium, 9840

4

Novartis Investigative Site

Genk, Belgium, 3600

Safety and Efficacy of Galvus in Elderly Type 2 Diabetes Patients | DecenTrialz