Status:
COMPLETED
This Study Will Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding In Brain Using PET (Positron Emission Tomography) In Healthy Volunteers
Lead Sponsor:
Pfizer
Collaborating Sponsors:
Yale University
Conditions:
Healthy
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to evaluate the relationship between plasma drug levels and receptor binding in brain using PET; and to evaluate safety and tolerability after a single administration of P...
Eligibility Criteria
Inclusion
- Healthy male and/or female subjects of nonchildbearing potential between the ages of 18 and 55 years, inclusive
Exclusion
- Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease.
- History of regular alcohol consumption exceeding 7 drinks/week for females or 14 drinks/week for males (1 drink = 5 ounces (150 mL) of wine or 12 ounces (360 mL) of beer or 1.5 ounces (45 mL) of hard liquor) within 6 months of screening
- Fulfillment of any of the MRI contraindications on the standard radiography screening questionnaire
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2011
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01258751
Start Date
December 1 2010
End Date
May 1 2011
Last Update
July 6 2011
Active Locations (3)
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1
Pfizer Investigational Site
New Haven, Connecticut, United States, 06511
2
Pfizer Investigational Site
New Haven, Connecticut, United States, 06519
3
Pfizer Investigational Site
New Haven, Connecticut, United States, 06520