Status:

TERMINATED

Cardiometabolic Risk of Shiftwork

Lead Sponsor:

University of Chicago

Conditions:

Sleep Deprivation

Circadian Dysregulation

Eligibility:

All Genders

18-50 years

Brief Summary

The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than...

Eligibility Criteria

Inclusion

  • Day workers and shift workers at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center who have maintained their work schedule (at least 30 hours/week) for at least 6 months.
  • Individuals who have been shift workers for less than 10 years; body mass index \<40 kg/m2;
  • No major illness
  • No history of psychiatric, endocrine, cardiac or sleep disorders
  • Those with hypertension or dyslipidemia will be included if these conditions are controlled by a stable treatment.
  • Women taking oral contraceptive or hormonal replacement therapy will be included only if they plan to stay on a stable regimen throughout the study.
  • Age must be between 18 and 50 years

Exclusion

  • Individuals who have worked at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center in their current position for less than 6 months.
  • Individuals who have been shift workers for more than 10 years
  • BMI\>40 kg/m2
  • Individuals with a major illness (e.g. diabetes, sleep disorder)

Key Trial Info

Start Date :

August 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT01264913

Start Date

August 1 2009

End Date

March 1 2015

Last Update

October 3 2016

Active Locations (1)

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1

The University of Chicago

Chicago, Illinois, United States, 60637