Status:
TERMINATED
Thyroid Cancer Among Chornobyl Clean-up Workers in Ukraine: Pilot Study
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Thyroid Cancer
Eligibility:
MALE
18-65 years
Brief Summary
Background: \- The Ukrainian Research Center for Radiation Medicine and the U.S. National Institutes of Health have been studying cancer risks and outcomes in individuals who participated in the deco...
Detailed Description
Background: Much is known about the radiation-related risk of thyroid cancer, but there is considerable uncertainty about the magnitude of the radiation risk among those who were exposed as adults, p...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- For the pilot study, we will select clean-up workers with thyroid cancer reported in three study areas, Kyiv, Donetsk and Dnipropetrovsk oblasts and controls (with a case-control ratio of 1:3) demographically matched to cases. We estimate the number of these cases will be between 100 and 110. These two oblasts have been chosen to represent an area known, from the leukemia study, to have a high study participation rate (Kyiv and Dnipropetrovsk oblasts) and an area newly added and thus unknown regarding participation rate (Donetsk). All study subjects are males and average about 55 years. In view of the very high survival rate for thyroid cancer, a majority of the subjects are expected to be alive.
- EXCLUSION CRITERIA:
- Excluded from the study will be those who cannot be located, refuse to participate in the study, or do not provide informed consent.
Exclusion
Key Trial Info
Start Date :
December 22 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 26 2020
Estimated Enrollment :
673 Patients enrolled
Trial Details
Trial ID
NCT01265381
Start Date
December 22 2010
End Date
February 26 2020
Last Update
March 3 2020
Active Locations (1)
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1
Research Center for Radiation Medicine
Kiev, Ukraine