Status:

COMPLETED

Positron Emission Tomography (PET) Amyloid Imaging of the Brain in Healthy Young Adult Subjects

Lead Sponsor:

GE Healthcare

Collaborating Sponsors:

i3 Statprobe

Medpace, Inc.

Conditions:

Healthy

Eligibility:

All Genders

18-40 years

Phase:

PHASE3

Brief Summary

Amyloid is an abnormal chemical found in the brain of patients with Alzheimer's Disease (AD). The study drug helps produce pictures of amyloid in the brain. The purpose of this study is to determine h...

Eligibility Criteria

Inclusion

  • The subject age is 18 to 40 years.
  • The subject has no evidence of thinking or memory problems by medical history.
  • The subject has a normal MRI scan.
  • The subject's general health is adequate to comply with study procedures.
  • The subject is willing and able to participate in all study procedures.

Exclusion

  • The subject has received any medical ionizing radiation exposure in the last 12 months (except planar x-ray or head CT).
  • The subject has a contraindication for (cannot undergo) MRI.
  • The subject has a history of head injury with loss of consciousness.
  • The subject has any significant medical, psychiatric or neurological condition that might be associated with brain pathology.
  • The subject has a family history of Alzheimer's Disease (AD); more than 1 first-degree relative.

Key Trial Info

Start Date :

December 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2011

Estimated Enrollment :

218 Patients enrolled

Trial Details

Trial ID

NCT01265394

Start Date

December 1 2010

End Date

April 1 2011

Last Update

July 2 2013

Active Locations (1)

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1

GE Healthcare

Princeton, New Jersey, United States, 08540