Status:
COMPLETED
Topical 0.05% Clobetasol Propionate in Vaseline Versus UVA-1 Phototherapy in Vulvar Lichen Sclerosus
Lead Sponsor:
Ruhr University of Bochum
Conditions:
Vulvar Lichen Sclerosus
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Lichen sclerosus is a rare, chronic cutaneous disorder with a predilection for the genital area. Any age group may be affected, although it is seen more often in postmenopausal women. The current gold...
Detailed Description
Genital lichen sclerosus is a rare chronic inflammatory connective tissue disease. The association with other autoimmune diseases and the detection of autoantibodies against ECM-1 point to an autoimmu...
Eligibility Criteria
Inclusion
- patients with genital lichen sclerosus
- Age \> 18 years
- Willingness to participate in this study
- No topical steroids within the last 4 weeks
Exclusion
- Age \< 18 years
- Known photodermatosis (eg, solar urticaria, polymorphous light eruption)
- Known genodermatosis with UV-sensitivity
- Treatment with photosensitizing drugs
- History of skin cancer
- significant UV exposure 3 months before study entry
- application of UV radiation therapies outside of the study conducted by UV irradiation: as: PUVA, UVA (including UVA1), UVB (including SEA) in the last 4 weeks before study entry or during the study period
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01400022
Start Date
August 1 2010
End Date
February 1 2013
Last Update
May 30 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Dermatology, Ruhr University Bochum
Bochum, North Rhine-Westphalia, Germany, 44791