Status:
COMPLETED
Bioavailability of Chlorogenic and Phenolic Acids From Soluble Coffees
Lead Sponsor:
Société des Produits Nestlé (SPN)
Conditions:
Healthy
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
Coffee contributes to a large extent to our daily intake of phenolic compounds which have been associated with potential health benefits. A study by Richelle et al. (2001), using an LDL oxidation assa...
Detailed Description
Coffee contributes to a large extent to our daily intake of phenolic compounds which have been associated with potential health benefits. A study by Richelle et al. (2001), using an LDL oxidation assa...
Eligibility Criteria
Inclusion
- 20 - 60 years, male and female
- healthy as determined by the medical questionnaire and the medical visit
- normal weight: BMI 19 - 25
- Coffee drinkers with an average consumption of 2-5 cups per day
- having given informed consent
Exclusion
- Intestinal or metabolic diseases / disorders such as diabetic, renal, hepatic, hypertension, pancreatic or ulcer
- food allergy
- Have had a major gastrointestinal surgery
- Difficulty to swallow
- Have a regular consumption of medication
- Have taken antibiotic therapy within the last 6 months
- Alcohol consumption \> 2 units a day
- Smokers \> 5 cigarettes a day
- Have given blood within the last 3 weeks before the start of the study
- Volunteers who cannot be expected to comply with treatment
- Currently participating or having participated in another clinical trial during the last 3 weeks
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01400386
Start Date
November 1 2010
End Date
June 1 2013
Last Update
May 22 2014
Active Locations (1)
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1
NESTEC/Clinical Development Unit / Metabolic Unit
Lausanne, Canton of Vaud, Switzerland, 1000