Status:

COMPLETED

Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules

Lead Sponsor:

Boston Medical Center

Collaborating Sponsors:

Fraunhofer USA

Conditions:

Cancer

Thyroid

Eligibility:

All Genders

18-80 years

Brief Summary

This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen. This is the next step in the research th...

Detailed Description

Background: Thyroid cancer is the most common endocrine malignancy. The current gold standard, fine-needle aspiration (FNA) biopsy, yields approximately 10-25% of indeterminate results, leading to pat...

Eligibility Criteria

Inclusion

  • Subjects undergoing thyroid biopsy for thyroid nodules, thyroid cancer, and thyroid goiter with nodules. Only those patients requiring sampling under established standard of care criteria and already scheduled to undergo biopsy for clinical purposes will undergo optical biopsy at the same time as their physical biopsy.

Exclusion

  • Subjects with nodules smaller than 1 cm, infectious diseases, on medication (such as coumadin) that may interfere with optical readings

Key Trial Info

Start Date :

June 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT01401855

Start Date

June 1 2011

End Date

June 1 2014

Last Update

June 17 2016

Active Locations (1)

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1

Boston Medical Center

Boston, Massachusetts, United States, 02118