Status:
COMPLETED
Optical Coherence Tomography (OCT) to Evaluate Cardiac Allograft Vasculopathy (CAV) in Patient's Post Heart Transplant
Lead Sponsor:
Columbia University
Conditions:
Cardiac Allograft Vasculopathy
Eligibility:
All Genders
18+ years
Brief Summary
Cardiac allograft vasculopathy (CAV) is a unique form of accelerated plaque formation seen in the coronary arteries of patients who have received heart transplantation. It is a major cause of morbidit...
Detailed Description
This study will involve imaging up to 100 patients at different points in time post heart transplant as part of their standard of care, with various degrees of disease and with different lesion subtyp...
Eligibility Criteria
Inclusion
- Post heart transplant patients
- Patients presenting for their routine annual or clinically indicated coronary angiogram post-heart transplant. The decision for coronary angiogram will be made by the treating physician from the heart-failure-transplant team (not by the physician who will do the angiogram)
- Clinically suspect or evidence of CAV in previous coronary angiogram
- Age \> 18
- Written informed-consent obtained
Exclusion
- Any complications that occur during routine biopsy of the coronary arteries during the same cath-lab visit
- Baseline renal failure with Cr \> 1.8
- Contraindication for anticoagulation
- Any other condition that in the opinion of the investigators would alter the safety of participation, or interfere with the ability to adhere to study procedures.
Key Trial Info
Start Date :
August 18 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01403142
Start Date
August 18 2011
End Date
January 1 2017
Last Update
August 31 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Columbia University Medical Center
New York, New York, United States, 10032