Status:
UNKNOWN
Study of the Effect of N-acetyl Cysteine on the Renal Graft Function Biomarkers (IL18, NGAL)
Lead Sponsor:
Shahid Beheshti University of Medical Sciences
Conditions:
Disorder Related to Renal Transplantation
Eligibility:
All Genders
Phase:
PHASE3
Brief Summary
The purpose of this study is to investigate the effect of (NAC) N-Acetyl Cysteine on biomarkers of Delayed Graft Function (DGF), including Neutrophil Gelatinase Associated Lipocalin (NGAL) and Interel...
Detailed Description
Kidney transplantation is the best treatment for most patients with end stage renal failure, but limited numbers of suitable kidneys are available for transplantation. So preservation of graft is vita...
Eligibility Criteria
Inclusion
- patient receiving transplantation from living donors
Exclusion
- having a neoplastic disease
- brain tumor
- having inflammatory diseases in their active phase (SLE)
- an acute infection, meningitis, sepsis
- Sickle Cell Disease
- Pregnancy
- Cardio-renal syndrome
- endogenous Cushing's syndrome
- chronic use of cimetidine
- a history of acute pancreatitis in recent months
- Multiple Sclerosis
- cardiac bypass in a recent month
- cirrhosis due to Hepatitis C
- having Alzheimer's disease
- having a untreated major depressive illness or schizophrenia
- Stroke in recent months
- Hyperoxaluria
- sensitivity to sulfonamides
Key Trial Info
Start Date :
April 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2012
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01403506
Start Date
April 1 2011
End Date
November 1 2012
Last Update
July 27 2011
Active Locations (1)
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1
Department of Nephrology, Shahid Labbafinejad Medical Center and Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences
Tehran, Tehran Province, Iran